01 / MUSCLE BIOLOGY
Muscle
Human and preclinical studies examine mitochondrial function, muscle strength and exercise capacity. Outcomes remain under active investigation.
Discuss a research brief ↗Urolithin A
Manufacturer:
Samples &
Commercial Supply
Research-led Urolithin A ingredients for formulation, technical evaluation and qualified B2B procurement.
CAS 1143-70-098% / 99% HPLC routes*Research laboratory + own manufacturing facilityCOA + sample review
*Confirm current lot specification before quotation.01 / 05
WHY THIS PLATFORM EXISTS
A research question
that starts in the gut.
Urolithina Lab was established around a translational question: how can a gut microbiota-derived metabolite be studied with the same rigour applied to any defined bioactive ingredient?
Research first established Urolithin A as a product of ellagitannin metabolism, then connected it with mitophagy and mitochondrial quality control in model systems. Our platform carries that work forward through analytical characterisation, mitochondrial endpoint testing and evidence-led ingredient development — keeping laboratory findings, human data and commercial specifications in their proper context.
Review the Urolithin A profile01Microbiota-derived
metabolite
metabolite
02Mitophagy and
muscle research
muscle research
03Human evidence
still developing
still developing
WHY UROLITHIN A
Mitochondrial quality control
changes across the lifespan.
Age-related mitochondrial decline is not a single event. It is a progressive research problem involving turnover, respiration and cellular energy capacity.
Mitochondria are the central entry point for our Urolithin A research. We ask whether damaged mitochondria are being cleared, whether cellular respiration and ATP production change, and whether those responses can be reproduced across relevant models.
Our laboratory evaluates mitochondrial respiration, ATP, membrane potential, oxidative stress, morphology and mitophagy flux. These endpoints connect mechanism research with Urolithin A raw-material evaluation, formulation screening and functional product development.
01
Upstream precursors
Ellagitannins and ellagic acid from foods such as pomegranate are starting materials — not Urolithin A itself.
02
Microbial metabolite
Certain gut microbes transform these compounds into urolithins, creating a molecule that can be isolated and characterised.
03
Mitochondrial question
Cell, animal and early human studies now examine mitophagy, muscle biology, safety and selected functional endpoints.
RESEARCH APPLICATIONS
Urolithin A
Research Applications.
We track where the evidence is strongest, where it is emerging and what still needs to be tested.
02 / IMMUNE & INFLAMMATION
Immune
Cell and preclinical models study inflammatory signalling and immune-cell responses. These findings are mechanistic, not treatment claims.
Discuss a research brief ↗03 / SKIN & CELLULAR HEALTH
Skin
Early translational work explores skin-related mitochondrial function and extracellular-matrix models. Human efficacy requires further controlled research.
Discuss a research brief ↗FORMULATION STARTERS
Built to be
formulated with.
Urolithin A is a crystalline powder with low water solubility. Whether it disperses evenly, survives your process and still reads uniform at release depends on the system you build around it — not on the certificate alone. These are the bench starting points our technical team works from with formulators.
01
Hard capsule — direct blend
UA 30% w/w of fill · microcrystalline cellulose q.s. · colloidal silicon dioxide 0.5% · magnesium stearate 0.75%Low-shear blend, 10–15 minutes. Size the capsule from the tapped density of your finished blend, not the raw powder.
02
Tablet — granulated
UA 40% w/w · PVP K30 3% (binder, aqueous) · MCC and lactose q.s. · croscarmellose sodium 3% · magnesium stearate 0.75%A low-solubility crystalline payload needs a binder and a disintegrant. Check content uniformity across the whole compression run, not only at the start.
03
Stick pack and RTD powder
UA 20% w/w · agglomerated base q.s. · acidity and flavour to profile · colloidal silicon dioxide 0.5% as flow aidSettling is a particle-size question. A finer grade disperses faster and settles softer — ask for the D50 range before you fix the fill weight.
04
Gummy — pectin, low-temperature deposit
UA 15% w/w · pectin–sucrose base q.s. · citric acid to pH 3.2–3.6 · colour and flavour to profileCook and hold temperatures matter. Run a short thermal hold test on your own base before assuming the payload comes through the deposit unchanged.
05
Oil suspension and softgel
UA 12% w/w · MCT or high-oleic sunflower oil q.s. · lecithin 1% as wetting agent · fumed silica 1–2% as anti-settlingWet the particle before you thicken the oil. Homogeneity in a suspension is a milling question first and a viscosity question second.
Loadings are w/w of the relevant phase and are bench starting points for development work — not intake or dosage guidance. Confirm every number against our TDS and your own trial data, and set the final specification for your market.
BUYER REVIEW
Why buyers choose Urolithina Lab
Choose an ingredient partner by checking the material, the evidence behind a lot and the terms of a supply brief. Start with the Urolithin A powder overview, review the quality and batch evidence, prepare a procurement brief and read the research context before drawing product conclusions.
| Decision | Evidence to check | Next step here |
|---|---|---|
| Select a grade | Assay method, lot COA, related substances and the target application. | Compare the stated 98% route with any available 99% lot before requesting a quote. |
| Qualify a sample | Sample-lot identity, specification, packaging and the buyer's own retest plan. | Ask for the current document set and link the sample to the same lot record. |
| Plan supply | Destination market, quantity, pack size, timing and agreed release criteria. | Send one complete brief so technical and commercial questions can be reviewed together. |
These are review steps, not a substitute for a current specification, customer audit or market approval.
OUR POINT OF VIEW
Less noise.
More useful
ingredient science.
/ CLARITY · RIGOUR · PARTNERSHIP
01
Own manufacturing facility
Urolithin A is produced in our own facility, with batch traceability from raw material to released lot.
02
Flexible batch scale
Development kilos through commercial quantities are scaled within the same facility and quality system.
03
Integrated QC panel
Identity, assay, residual solvents, heavy metals and microbial controls are tested and reported with each COA.
04
Audit support
Supplier qualification, documentation and audit support are available on request.
COMMON QUESTIONS
A practical
starting point.
Answers for first conversations. Share your brief for product-specific information.
What is Urolithin A?
Urolithin A is a metabolite generated from ellagitannin compounds by certain gut microbes. It is being studied in mitochondrial biology and is available as a defined ingredient for qualified product-development review.
What information can I request?
Buyers can request a product specification, COA example, available test parameters, sample options, packaging details and a documentation checklist for internal review.
Which formats can be explored?
Capsule, powder, sachet and functional food or beverage concepts can be discussed. The right format depends on the target market, sensory brief, stability needs and finished-product process.
Is this consumer health advice?
No. This website is for B2B ingredient sourcing and formulation conversations. It does not provide diagnosis, treatment, prevention, dosage or consumer-use recommendations.
START A CONVERSATION
Bring your brief.
We’ll bring clarity.
Tell us your target format, market, purity route and documentation needs.